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Primary infertility When a woman is unable to ever bear a child, either due to the inability to become pregnant or the inability to carry a pregnancy to a live birth she would be classified as having primary infertility. Endometrial biopsy should be performed only in women with suspected pathology (chronic endometritis or neoplasia). Metformin (Glucophage): If Clomifene is not effective, metformin may help women with PCOS, especially when linked to insulin resistance.

Drawbacks of ICSI include unknown risks to the egg or embryo and damage to the embryo. Products include enzymes and proteases to liquefy the seminal coagulum. Gonadotropin-releasing hormone (Gn-RH) analogs: These can help women who ovulate too early—before the lead follicle is mature—during hmG treatment.

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To help objectify sperm morphology and therefore enhance the consistency and reproducibility among laboratories, Kruger introduced a definition of "strict criteria" in 1986. Ongoing Pregnancies and Birth after Intracytoplasmic Sperm Injection with Frozen-thawed Epididymal Spermatozoa. (PDF, 442 KB) Human Reproduction, 1995.

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If each step has occurred as planned, implantation of the fertilized egg into the uterus can take place within 72 hours of the ICSI process. Fertility treatments for women Fertility drugs might be prescribed to regulate or induce ovulation. 8,46 Obesity impairs fertility and the response to fertility treatments, including in vitro fertilization; therefore, it is advisable to counsel patients who are obese to lose weight before conception or infertility treatments. As the major causes of infertility are sperm abnormalities, ovulation dysfunction, and fallopian tube obstruction, the preliminary adviced investigations for the infertile couple should be focused on semen analysis (to be compared with the WHO reference values [27]), detection of ovarian function by hormonal assay (early follicular FSH and LH levels, and mid-luteal progesterone), and evaluation of tubal patency by hysterosalpingography (HSG) [17-32], (Appendix 3). In the 1980s, a pure form of FSH became available.

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Microsurgical Aspects of Varicocele. (PDF, 9 MB) Fertility and Sterility, 1979. It is better for a couple to see the doctor together. In these methods, fertilization occurs inside the body. The feelings experienced by the infertile couples include depression, grief, guilt, shame, and inadequacy with social isolation. Production of the First Offspring from Oocytes Derived from Fresh and Cryopreserved Pre-antral Follicles of Adult Mice. (PDF, 2 MB) Reproductive BioMedicine Online, 2007. Abnormality in any of those regions may indicate abnormal sperm function and compromise the ability of sperm to fertilize the egg. As a result, estrogen levels are dramatically reduced, releasing the hypothalamic-pituitary axis from its negative feedback. Basal body temperatures are no longer considered a reliable indicator of ovulation, and are not recommended for evaluating ovulation. Intrauterine insemination is a process by which sperm is washed and prepared for placement into the uterine cavity, therefore bypassing the cervix and bringing a higher concentration of motile sperm closer to the tubes and ovulated egg. Patients who do not ovulate because of a fault in the pituitary gland may receive this drug as an injection. It varies with the age (the optimal female age is between 23 and 39 years) and with body weight (the ideal body mass index is between 19 and 30). A history of pelvic infections or sexually transmitted diseases: Sexually transmitted infections, such as chlamydia or gonorrhea, can cause inflammation and permanent scarring of the fallopian tubes. Treatment The cost of infertility treatment is high [34].