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The prevalence varies widely, being less in developed countries and more in developing countries where limited resources for investigation and treatment are available [2]. Couples may decide to go ahead regardless if the desire to become pregnant is very strong. Especially in men, psychological explanations should be considered as they are frequently the cause of sexual dysfunctions. Ovulation of the egg occurs approximately 2 weeks before the start of the next period. The patient should be abstinent for 2-3 days prior to maximize sperm number and quality. The administration of hMG and its derivatives should be under the direct supervision of a reproductive endocrinologist.

As the duration of treatment prolonged, psychological suffering is likely to increase [6]. Couples who do not conceive after treatment for six cycles with documented ovulation should also consider referral to an infertility specialist. If ovulation does not occur with the 50-mg dose, the CC dose must be increased in subsequent cycles to 100 mg for 5 days. According to ESHRE recommendations, couples with an estimated live birth rate of 40% or higher per year are encouraged to continue aiming for a spontaneous pregnancy.[66] Treatment methods for infertility may be grouped as medical or complementary and alternative treatments.

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Female age of 35 years or older: For unclear reasons, egg numbers decrease at a rapid rate as women age. The most common disorders impacting ovulation include polycystic ovary syndrome (PCOS), hypogonadotropic hypogonadism (from signaling problems in the brain), and ovarian insufficiency (from problems of the ovary). Additionally, surgery, radiation or chemotherapy to treat tumors can affect male fertility.

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The starting dose is 5 mcg per pulse intravenously or 5-25 mcg subcutaneously. Minimal Ovarian Stimulation (mini-IVF) for IVF Utilizing Vitrification and Cryopreserved Embryo Transfer. (PDF, 406 KB) Reproductive BioMedicine Online, 2010. The couple should have sex at least every two days between the 10th and 18th day after the woman starts her period.

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Happily, many couples treated for infertility go on to have babies. Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions. A mouse study has suggested that ingredients in some household detergents may reduce fertility. However, further testing may include: A general physical exam by a urologist. The chance of a live birth following treatment is nearly 50% [25]. 0.[44] Environmental factors Toxins such as glues, volatile organic solvents or silicones, physical agents, chemical dusts, and pesticides.[45][46] Tobacco smokers are 60% more likely to be infertile than non-smokers.[47] German scientists have reported that a virus called adeno-associated virus might have a role in male infertility,[48] though it is otherwise not harmful.[49] Other diseases such as chlamydia, and gonorrhea can also cause infertility, due to internal scarring (fallopian tube obstruction).[50][51][52] Alimentary habits[53] Obesity: The obesity epidemic has recently become is a serious issue, particularly in industrialized nations. Women attempting pregnancy at age 40 or older have a 50% decreased fertility rate and a two-fold to three-fold increased risk of spontaneous abortion compared with younger women. Endometriosis causes infertility by producing inflammation and scarring, which can result in not only pain but also potentially detrimental effects on egg, sperm or embryo. Paternal age > or = 40 years: an important risk factor for infertility. However, these tests have only poor to moderate predictive value despite widespread use. 50% are female causes with 25% being due to anovulation and 25% tubal problems/other.[74] In Sweden, approximately 10% of couples wanting children are infertile.[75] In approximately one third of these cases the man is the factor, in one third the woman is the factor, and in the remaining third the infertility is a product of factors on both parts.


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