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It has been suggested that infertility be classified as a form of disability.[22] Causes[edit] Immune infertility[edit] Antisperm antibodies (ASA) have been considered as infertility cause in around 10–30% of infertile couples.[23] In both men and women, ASA production are directed against surface antigens on sperm, which can interfere with sperm motility and transport through the female reproductive tract, inhibiting capacitation and acrosome reaction, impaired fertilization, influence on the implantation process, and impaired growth and development of the embryo. The test is rated positively when motile sperm can be proved in the mucus.

London, United Kingdom: National Institute for Health and Clinical Excellence (NICE); February 2013:1–63. (Clinical guideline no. ICSI with Epididymal and Testicular Sperm in Azoospermic Men. (PDF, 2 MB) From Treatment of Infertility: The New Frontiers, 1998. 8 However, if your doctor diagnoses you with infertility, then it’s likely that you’ll need some additional help to conceive.  This may be as simple as timing when you have sex, or you may need more advanced fertility treatment.   Discovering that you’re infertile can be overwhelming, but the right support can help you to conceive successfully. 8 Counseling on lifestyle modifications is reasonable because exposures to tobacco and alcohol are associated with lower rates of fertility.

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Clomiphene citrate (Clomid, Serophene) The chemical formula for clomiphene citrate (CC) is 2-[p -(2-chloro-1,2-difhenylvinyl) phenoxy] triethylamine dihydrogen citrate. Normal seminal fructose concentration is 120-450 mg/dL, with lower levels suggesting ejaculatory duct obstruction or absence of the seminal vesicles. 25 Women with no clear risk of tubal obstruction should be offered hysterosalpingography to screen for tubal occlusion and structural uterine abnormalities. It will take time until these studies can be available for clinics and patients as a regularity. The sperm must provide the zygote with DNA, centrioles, and activation factor for the embryo to develop.

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Mumps: If this occurs after puberty, inflammation of the testicles may affect sperm production. Tubal occlusion is a cause of infertility because an ovulated egg is unable to be fertilized by sperm or to reach the endometrial cavity. Treatment is with human menopausal gonadotropin (HMG) or exogenous FSH.

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Society and culture[edit] Perhaps except for infertility in science fiction, films and other fiction depicting emotional struggles of assisted reproductive technology have had an upswing first in the latter part of the 2000s decade, although the techniques have been available for decades.[76] Yet, the number of people that can relate to it by personal experience in one way or another is ever growing, and the variety of trials and struggles is huge.[76] Pixar's Up contains a depiction of infertility in an extended life montage that lasts the first few minutes of the film.[77] Other individual examples are referred to individual subarticles of assisted reproductive technology Ethics[edit] There are several ethical issues associated with infertility and its treatment. Success rates for induction of ovulation vary considerably and depend on the age of the woman, the type of medication used, the presence of other infertility factors present in the couple and other reasons. IVF was a major breakthrough because it allowed for successful pregnancies in women that were previous deemed permanently infertile, such as when the fallopian tubes are both markedly damaged. Women who are at risk, including those on a vegan diet, should ask the doctor about supplements.