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Erectile dysfunction, vaginismus (painful involuntary spasm of vagina preventing intercourse) and dyspareunia (pain during sexual intercourse) can explain involuntary childlessness in some couples. Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens. (PDF, 5 MB) New England Journal of Medicine, 1995. The Takeaway Around 15 to 20 percent of couples trying to conceive will have trouble with infertility. Although the sperm count may be slightly decreased by an intercourse frequency of once per day or once every other day, the motility and number of sperm in the healthy male would be sufficient to achieve pregnancy. Varicocele A varicocele is a swelling of the veins that drain the testicle, which can impact sperm quality. Renal Transplantation Between Adults and Children. (PDF, 1 MB) Journal of the American Medical Association, 1974.

Hypospadias: The urethral opening is under the penis, instead of its tip. Vasectomy Reversal. (PDF, 733 KB) The New England Journal of Medicine, 1977.

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Some problems stop an egg being released at all, while others prevent an egg being released during some cycles but not others. At the same time, the number of pregnancy losses and malformations in the foetus increase. Kidney Transplantation in Inbred Rats. (PDF, 6 MB) The American Journal of Surgery, 1973.

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In order to perform ICSI, an egg is held via a small suction pipette, while one sperm is injected into that egg using a very fine glass needle. In general, infertility is defined as the inability of couples to achieve pregnancy after ≥1 year of trying (1). Bhaskar Dutta/Photoshare Clinical definitions Infertility is “a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse.”… (WHO-ICMART glossary1). “Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year.

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Women trying to conceive often have depression rates similar to women who have heart disease or cancer.[18] Emotional stress and marital difficulties are greater in couples where the infertility lies with the man.[19] Older people with adult children appear to live longer.[20] Why this is the case is unclear and may dependent in part on those who have children adopting a healthier lifestyle, support from children, or the circumstances that led to not having children.[20] [edit] In many cultures, inability to conceive bears a stigma. Obesity can increase the risk for other conditions that may impact a man's fertility such as sperm quality and sexual dysfunction. Infectious, anatomic, metabolic, and functional problems associated with infertility are seen less frequently. (Also see Infertility.) The only confirmed infectious cause of infertility in the bitch is brucellosis (see Brucellosis in Dogs). Treatment of tubal obstruction generally requires referral for subspecialty care. ART: Intracytoplasmic Sperm Injection (ICSI) Another ART procedure  Intracytoplasmic Sperm Injection (ICSI)  involves the injection of a single sperm into the egg. The main side effects are hot flushes, gastrointestinal events (nausea and vomiting), headache, back pain, and leg cramps. Changes in sexual desire A man’s fertility is also linked with his hormone health. Abdominal myomectomy is a surgical procedure performed through a very low horizontal abdominal incision allowing access to the uterus for removal of fibroids. In closed social groups, a degree of rejection (or a sense of being rejected by the couple) may cause considerable anxiety and disappointment. Women 35 and older should see their doctor after six months of trying.