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Mixed gonadal dysgenesis (45, X/46, XY) Patients usually have ambiguous genitalia, a testis on one side, and a streaked gonad on the other. Infertility may be caused by blockage of the Fallopian tube due to malformations, infections such as chlamydia or scar tissue. Microsurgery for the Undescended Testicle. (PDF, 5 MB) Urologic Clinics of North America, 1982.

Infertility might contribute to stress, anxiety, and depression in couples trying to conceive, and treatment can be medically invasive and expensive. A urine sample must be collected immediately after ejaculation. When the magic moment arrives, about 150 million sperm are ejaculated in a half-teaspoon of semen through the penis.

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Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. These tests are used to determine gland failure or obstruction. Signs of infertility include irregular, excessively heavy, or absent periods as well as sudden weight gain, painful sex, or vaginal infections. Idiopathic Hypercalciuria. (PDF, 1 MB) New England Journal of Medicine, 1971. Similarly, bilateral obstruction of the sperm ducts can cause azoospermia and infertility. Peripheral organ The hypothalamus-pituitary axis may be interrupted by hormonally active peripheral tumors or other exogenous factors, due to cortical excess, cortical deficiency, or estrogen excess.

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If necessary, they refer patients to a fertility clinic or local hospital for more specialized tests. The idea is that for women beyond age 35, every month counts and if made to wait another six months to prove the necessity of medical intervention, the problem could become worse. Renal Transplantation Between Adults and Children. (PDF, 1 MB) Journal of the American Medical Association, 1974. Additionally, the quality of her eggs also decreases increases the chance of chromosomal abnormalities. This may take the form of miscarriages or extrauterine pregnancies. Surgical Management of Male Infertility. (PDF, 2 MB) Chapter 12 from textbook, Male Infertility, 1992.

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Religious leaders' opinions on fertility treatments; for example, the Roman Catholic Church views infertility as a calling to adopt or to use natural treatments (medication, surgery, or cycle charting) and members must reject assisted reproductive technologies. If necessary, they refer patients to a fertility clinic or local hospital for more specialized tests. Artificial Insemination In this process, male sperm is introduced into the female genital tract in order to achieve fertilization. A urinary LH kit is a practical way to monitor these patients. Heavy, long, or painful periods Heavy periods may indicate an underlying condition affecting fertility.