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Worldwide, 8 to 12 percent of couples experience fertility problems. The enzyme aromatase is responsible for this conversion, and is found primarily in adipose tissue. Previous sterilization treatment: In women who have chosen to have their fallopian tubes blocked, the process can be reversed, but the chances of becoming fertile again are not high. Intra-uterine insemination for male subfertility. Preliminary Tests of a New Reversible Male Contraceptive in Bush Dog, Speothos Venaticus: Open-ended Vasectomy and Microscopic Reversal. (PDF, 106 KB) Journal of Zoo and Wildlife, 2006.

Fertilization takes place outside the body, and the fertilized egg is reinserted into the woman's reproductive tract, in a procedure called embryo transfer. Male infertility tests: Going under the microscope Identifying the cause of a man's infertility is as much an art as a science. “The first step is an evaluation by a physician specializing in male infertility,” says Stephen Shaban, MD, a urologist specializing in male reproductive medicine and microsurgery in Raleigh, North Carolina. Primary vs. secondary infertility[edit] Primary infertility is defined as the absence of a live birth for women who desire a child and have been in a union for at least 12 months, during which they have not used any contraceptives.[14] The World Health Organisation also adds that 'women whose pregnancy spontaneously miscarries, or whose pregnancy results in a still born child, without ever having had a live birth would present with primarily infertility'.[15] Secondary infertility is defined as the absence of a live birth for women who desire a child and have been in a union for at least 12 months since their last live birth, during which they did not use any contraceptives.[15] Thus the distinguishing feature is whether or not the couple have ever had a pregnancy which led to a live birth. 6 The initial history should cover menstrual history, timing and frequency of intercourse, previous use of contraception, previous pregnancies and outcomes, pelvic infections, medication use, occupational exposures, substance abuse, alcohol intake, tobacco use, and previous surgery on reproductive organs.

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Fertilizing Capacity of Epididymal and Testicular Sperm with ICSI. (PDF, 5 MB) Frontiers in Endocrinology, 1995. Evaluation may be initiated sooner in patients who have risk factors for infertility or if the female partner is older than 35 years. Intracytoplasmic Sperm Injection and Infertility. (PDF, 53 KB) Nature Genetics, 2001. A decreased testosterone level with an increased FSH level points to primary hypogonadism. In closed social groups, a degree of rejection (or a sense of being rejected by the couple) may cause considerable anxiety and disappointment. Patients with severe ovarian hyperstimulation syndrome are often hospitalized and confined to bed, with strict control of fluid intake and output.

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Furthermore, myomas in the uterus lead to occlusions of the lumen and so cause sterility. Ejaculation disorders Ejaculation disorders include premature ejaculation, anejaculation (the failure to ejaculate), and retrograde ejaculation, which is when semen enters the bladder during orgasm instead of coming out the tip of the penis. Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994.

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6,23 Anovulatory women should have further investigation to determine treatable causes such as thyroid disorders or hyperprolactinemia based on symptoms. Malformation of the eggs themselves may complicate conception. The procedure is performed in an outpatient setting in the vast majority of cases, and recovery time can be as little as a few days. Uterine fibroids Fibroids are noncancerous growths in the uterus. The Relationship of Abnormal Semen Values to Pregnancy Outcome. (PDF, 770 KB) Chapter 10 from textbook, 1992. Use of clomiphene citrate in infertile women: a committee opinion. Infertility caused by DNA defects on the Y chromosome is passed on from father to son. Gerrits T, Shaw M (2010). "Biomedical infertility care in sub-Saharan Africa: a social science review of current practices, experiences and view points". Basal body temperatures are no longer considered a reliable indicator of ovulation, and are not recommended for evaluating ovulation. One-third of couples will discover fertility problems in both partners or will have their infertility remain unexplained. About 85% of couples will have had a pregnancy by that point. “If they are over 30, they should seek evaluation after six months.” Continued Common causes of male infertility The “male factor” contributes to infertility around half the time, and about one third of the time, it's the main cause of infertility. Testicular Transplantation and Autotransplantation. (PDF, 8 MB) Chapter 22 of textbook, Extracorporeal and Microvascular Surgery, 1982.