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Existing definitions of infertility lack uniformity, rendering comparisons in prevalence between countries or over time problematic. 10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. After stimulation, the physician surgically extracts one or more eggs from the ovary, and unites them with sperm in a laboratory setting, with the intent of producing one or more embryos. Environmental vs Genetic Sex Determination: A Possible Factor in Dinosaur Extinction? (PDF, 307 KB) Fertility and Sterility, 2004. Large submucosal uterine fibroids may make the uterus' cavity bigger, increasing the distance the sperm has to travel. The Three-kidney Rat Model. (PDF, 2 MB) Investigative Urology, 1974.

Several days later, embryos -- or fertilized eggs -- get put back into your uterus with a device called an intrauterine insemination catheter. Microsurgical Epididymal Sperm Aspiration and Assisted Reproductive Techniques. (PDF, 4 MB) Frontiers in Human Reproduction, 1991. Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair. Illegal drugs: Some women who use marijuana or cocaine may have fertility problems. A detailed history and physical examination is necessary for both partners.

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Follicle-stimulating hormone (Gonal-F, Bravelle): This hormone is produced by the pituitary gland that controls estrogen production by the ovaries. Additional tests to determine sterility include blood tests, an ultrasound of the ovaries, hysterosalpingography to check for physical problems of the uterus and fallopian tubes. Enzymatic Digestion of Testicular Tissue May Rescue the Intracytoplasmic Sperm Injection Cycle in Some Patients with Non-obstructive Azoospermia. (PDF, 66 KB) Human Reproduction, 1998. Assisted conception The following methods are currently available for assisted conception. Treatment of Male-factor Infertility. (PDF, 10 MB) Chapter 9 from Progress in Infertility, 1993. Ovulation disorders can be due to: Premature ovarian failure: The ovaries stop working before the age of 40 years.

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Image: “ICSI of marmoset oocytes after in vitro maturation.” by openi. 6,28 Additionally, postcoital testing of cervical mucus is no longer recommended because it does not affect clinical management or predict the inability to conceive. First Fallopian Tube-Ovary Transplant Carried Out. (PDF, 2 MB) Welcome Trends in Ob/Gyn, 1985. Many cases are treated with medication or may require surgical procedures.

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Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994. If oligospermia or azoospermia is noted, hypogonadism should be suspected. The Fate of Non-absorbable Intraureteral Suture. (PDF, 233 KB) The Journal of Urology, 1973. A Modern Approach to Male Infertility. (PDF, 2 MB) Serono Symposia, Insights Into Infertility Newsletter, 1997. Metformin (Glucophage) is another type of medication that may help you ovulate normally if you have insulin resistance or PCOS (polycystic ovarian syndrome). The AZFc Region of the Y Chromosome Features Massive Palindromes and Uniform Recurrent Deletions in Infertile Men. (PDF, 5 MB) Nature Genetics, 2001. Treatment of Anovulatory Conditions Jump to section + Women with WHO group I ovulatory disorders should be counseled to achieve a normal body weight. Quantitative Analysis of Testicle Biopsy: Determination of Partial Obstruction and Prediction of Sperm Count after Surgery for Obstruction. (PDF, 4 MB) Fertility and Sterility, 1981. Happily, many couples treated for infertility go on to have babies. Medical treatments[edit] Medical treatment of infertility generally involves the use of fertility medication, medical device, surgery, or a combination of the following.