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If a blockage is present, surgery may be necessary. Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous–Palaeogene boundary. (PDF, 238 KB) Biology Letters, 2010. Birth after Preimplantation Diagnosis of the Cystic Fibrosis F508 Mutation by Polymerase Chain Reaction in Human Embryos Resulting from Intracytoplasmic Sperm Injection with Epididymal Sperm. (PDF, 2 MB) The Journal of the American Medical Association, 1994. Intracytoplasmic sperm injection (ICSI.)A single sperm is injected through a tiny needle into an egg. United Kingdom[edit] In the UK, previous NICE guidelines defined infertility as failure to conceive after regular unprotected sexual intercourse for two years in the absence of known reproductive pathology.[11] Updated NICE guidelines do not include a specific definition, but recommend that "A woman of reproductive age who has not conceived after 1 year of unprotected vaginal sexual intercourse, in the absence of any known cause of infertility, should be offered further clinical assessment and investigation along with her partner, with earlier referral to a specialist if the woman is over 36 years of age."[12] Other definitions[edit] Researchers commonly base demographic studies on infertility prevalence on a five-year period.[13] Practical measurement problems, however, exist for any definition, because it is difficult to measure continuous exposure to the risk of pregnancy over a period of years.

The abdomen is usually insufflated with carbon dioxide gas. The rod-lens based laparoscopes dominate overwhelmingly in practice, due to their fine optical resolution (50 µm typically, dependant on the aperture size used in the objective lens), and the image quality can be better than that of the digital camera if necessary. Other medical techniques are e.g. tuboplasty, assisted hatching, and preimplantation genetic diagnosis. Secondary fertility involves one or both partners who have conceived previously, but are now unable to do so because of a possible physical or medical condition impairing fertility. This combination of laboratory test results may indicate ovarian insufficiency or diminished ovarian reserve. Cervical mucus problems impairing conception may be treated with intrauterine insemination (IUI) or uterine instillation of specially prepared sperm.

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In-vitro fertilization and donor insemination are major procedures involved. Surgical procedure to conserve the uterus for future pregnancy in patients suffering from massive adenomyosis.(PDF, 958 KB) Reproductive BioMedicine Online, 2010. Afterward, the embryo transfer follows with a sterile special catheter into the cavum uteri.

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For most specimens, the greatest recovery of the motile portion results from separation via centrifugal filtration through a discontinuous density gradient system. Sometimes, female infertility is related to a hormone problem.

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Hypospadias affects about 1 in every 500 newborn boys. Sperm count often returns to normal after stopping the medication. Paternal age > or = 40 years: an important risk factor for infertility. Mental stress: This may affect female ovulation and male sperm production and can lead to reduced sexual activity.