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Female age of 35 years or older: For unclear reasons, egg numbers decrease at a rapid rate as women age. About one-third of infertility cases are caused by fertility problems in men and another one-third of fertility problems are due to fertility problems in women.

Then, generally one or two embryos, which have demonstrated appropriate development, are carefully and gently transferred into the uterine cavity. Damaged Sperm Ducts: Seven percent of infertile men cannot transport sperm from their testicles to out of their penis.  This pathway may be blocked by a number of conditions: · A genetic or developmental mistake may block or cause the absence of one or both tubes (which   transport the sperm from the testes to the penis). · Scarring from tuberculosis or some STDs may block the epididymis or tubes. · An elective or accidental vasectomy may interrupt tube continuity. Factors Affecting Fertility (Continued) Among other factors affecting the probability of conception are: Age of women. Submucosal fibroids are the type if fibroid that has clearly been demonstrated to reduce pregnancy rate, roughly by 50%, and removal of which will double pregnancy rate. Religious leaders' opinions on fertility treatments; for example, the Roman Catholic Church views infertility as a calling to adopt or to use natural treatments (medication, surgery, or cycle charting) and members must reject assisted reproductive technologies.

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44 Therefore, a simple recommendation is for vaginal intercourse every two to three days to optimize the chance of pregnancy. Intrauterine insemination. For this procedure, after semen gets rinsed with a special solution, a doctor places it into your uterus when you're ovulating. Unexplained infertility is not the same thing as having no explanation, but rather reflects the fact that the tests performed have been normal.

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Chromosomal Abnormalities in Embryos Derived from Testicular Sperm Extraction. (PDF, 324 KB) Fertility and Sterility, 2003. Through this technique, your physician can diagnose abnormalities such as fibroids or polyps within the uterine cavity, and via narrow instruments that run through the hysterosope, can remove or correct the great majority of these abnormalities. Successful Pregnancy and Delivery after Calcium Ionophore Oocyte Activation in a Normozoospermic Patient with Previous Failed Fertilization after Intracytoplasmic Sperm Injection. (PDF, 57 KB) Fertility and Sterility, 2003. Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole. Done as part of an IVF treatment, ICSI involves injecting a single sperm into an egg.

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The laboratory evaluation begins with a semen analysis. Submucosal fibroids: Benign or non-cancerous tumors occur in the muscular wall of the uterus. If there's a problem with the mucus, it can make it harder to conceive. These injections are taken nightly, typically for 5 – 10 days, and act directly on the cells of the ovary to stimulate egg development. Its mechanism of action is still not well understood, but it competes for the estrogen receptor at the hypothalamus, pituitary, and ovarian levels. 8,37 Women in WHO group II, including those who are overweight and who have polycystic ovary syndrome, can benefit from weight loss, exercise, and lifestyle modifications to restore ovulatory cycles and achieve pregnancy. A low testosterone level with a low FSH level signals a secondary cause. Some causes, such as hyperprolactinemia, are reversible with proper treatment. Generally, evaluation should be offered to couples who have not conceived after one year of unprotected vaginal intercourse. Definition “A woman of reproductive age who has not conceived after 1 year of unprotected vaginal sexual intercourse, in the absence of any known cause of infertility” NICE guideline, CG156 Primary infertility; couple have failed to conceive before. Secondary infertility; woman has previously been pregnant regardless of the outcome of the pregnancy and now unable to conceive. For women, being underweight and having extremely low amounts of body fat are associated with ovarian dysfunction and infertility and they have a higher risk for preterm birth. The more fetuses there are, the higher the risk of premature labor.