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According to the literature survey, the most common causes of infertility are: male factor [5,7-9,13-15] such as sperm abnormalities [9,13,15], female factor [7-9,14-16] such as ovulation dysfunction [7,8] and tubal pathology [7-9], combined male and female factors [7,9,14,15] and unexplained infertility; where no obvious cause could be detected [7-9]. Pregnancy Caused by Sperm from Vasa Efferentia. (PDF, 1 MB) Fertility and Sterility, 1988. IVF and related techniques (ICSI, ZIFT, GIFT) are called assisted reproductive technology (ART) techniques.

Idiopathic Hypercalciuria. (PDF, 1 MB) New England Journal of Medicine, 1971. Blood test: This can assess hormone levels and whether a woman is ovulating. Wählen Sie „OK“, um fortzufahren und Oath und seinen Partnern zu erlauben, Ihre Daten zu verwenden, oder wählen Sie „Optionen verwalten“, um Ihre Auswahlmöglichkeiten anzuzeigen.Understanding fertility If you’ve been trying to conceive for a while, you may be wondering why your partner isn’t pregnant yet. If the correction is not done, it may be harder for the sperm to get to the female's cervix. Genetics of Male Infertility: Evolution of the X and Y Chromosome and Transmission of Male Infertility to Future Generations. (PDF, 10 MB) Chapter 5 from Essential IVF, 2004.

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Peripheral organ The hypothalamus-pituitary axis may be interrupted by hormonally active peripheral tumors or other exogenous factors, due to cortical excess, cortical deficiency, or estrogen excess. 6,23 Anovulatory women should have further investigation to determine treatable causes such as thyroid disorders or hyperprolactinemia based on symptoms. Negative tests with immotile sperm in the cervical mucus suggest rare immunological causes of sterility. In vitro fertilization (IVF). In this technique, your doctor places into your uterus that were fertilized in a dish. Some women have bilateral tubal occlusion, which is when both tubes are blocked.

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Medication. If you have ovulation problems, you may be prescribed drugs such as clomiphene citrate (Clomid, Serophene), gonadotropins (such as Gonal-F, Follistim, Humegon and Pregnyl), or letrozole. FSH stimulates the Sertoli cells to facilitate sperm production, while LH stimulates testosterone release from the Leydig cells. Fallopian tubes that are patent and will function to permit the sperm and ovum to meet and allow migration of the conceptus to the uterus. A lower concentration may lead to a lower chance for conception without treatment; 3) sperm motility or movement – a normal motility should be at least 50%. Optimal sperm conditions Although only one sperm is needed to fertilise your partner’s egg, the enzymes from multiple sperm are needed to break down the egg’s protective barrier. GIFT (gamete intrafallopian tube transfer) and ZIFT (zygote intrafallopian transfer).  Like IVF, these procedures involve retrieving an egg, combining it with sperm in a lab, and then transferring it back to your body.

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For intrauterine insemination, in vitro fertilization, and intracytoplasmic sperm injection procedures, the removal of certain components of the ejaculate (ie, seminal fluid, excess cellular debris, leukocytes, morphologically abnormal sperm) with the retention of the motile fraction of sperm is desirable. Problems in the uterus or fallopian tubes can prevent the egg from traveling from the ovary to the uterus, or womb. Fertility treatment with donor eggs is usually done using IVF. Metformin (Glucophage): If Clomifene is not effective, metformin may help women with PCOS, especially when linked to insulin resistance. Opinion: Microsurgical TESE and the Distribution of Spermatogenesis in Non-obstructive Azoospermia. (PDF, 5 MB)Human Reproduction, 2000. In 10% of cases, alterations in the chemical signals from the hypothalamus can easily seriously affect the ovaries. Normal sperm have a smooth oval head approximately 3-5 μm long and 2-3 μm wide. Abundant Gene Conversion Between Arms of Palindromes in Human and Ape Y Chromosomes. (PDF, 340 KB)Nature, 2003. For the past 20 years, hMG and its derivatives have been the first choice for controlled ovarian hyperstimulation in assisted reproductive technologies. The fertilized embryo is then transferred to womb. 3,4  Infertility may arise from male factors, female factors, or a combination of these (Table 15–8).