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Additional risk factors may include smoking, alcohol use, obesity, and older age; however, the data are hampered by a lack of pregnancy-related outcomes. The fertilized embryo is then transferred to womb. IVF in action Intracytoplasmic sperm injection (ICSI): A single sperm is injected into an egg to achieve fertilization during an IVF procedure.

After ruling out female infertility concerns, tests for male infertility may be needed. Testicular histology typically reveals a decreased number of Leydig cells and decreased spermatogenesis. 0.[44] Environmental factors Toxins such as glues, volatile organic solvents or silicones, physical agents, chemical dusts, and pesticides.[45][46] Tobacco smokers are 60% more likely to be infertile than non-smokers.[47] German scientists have reported that a virus called adeno-associated virus might have a role in male infertility,[48] though it is otherwise not harmful.[49] Other diseases such as chlamydia, and gonorrhea can also cause infertility, due to internal scarring (fallopian tube obstruction).[50][51][52] Alimentary habits[53] Obesity: The obesity epidemic has recently become is a serious issue, particularly in industrialized nations. The number of days in between each period varies each month.

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Cystic fibrosis CF is the most common genetic disorder in whites. Endocrine tests to check concentrations of the hormones testosterone, FSH and LH. Seventy-five percent of patients have testicular atrophy and primary testicular failure due to degeneration of the seminiferous tubules. Poor egg quality: Eggs that are damaged or develop genetic abnormalities cannot sustain a pregnancy. An estimated 28% of all couples seeking reproductive assistance may have normal findings on their clinical evaluation, making the unexplained infertility a more common provisional diagnosis.

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A Physical Map of the Human Y Chromosome. (PDF, 160 KB) Nature, 2001. It is specially oriented for cancer patients, whose sperm is destroyed due to the gonadotoxic treatment they are submitted to.[70] Ovaric stem cells: it is thought that women have a finite number of follicles from the very beginning.

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Fibroids should be treated if they are associated with abnormal uterine bleeding or if they are thought to be the cause of infertility. Men with Infertility Caused by AZFc Deletion can Produce Sons by Intracytoplasmic Sperm Injection, but are Likely to Transmit the Deletion and Infertility. (PDF, 102 KB) Human Reproduction, 1999. It does not affect the couples' life only, but it also affects the healthcare services and social environment [4]. Only active, undamaged sperm are chosen for injections.


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