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These may be purchased over the counter and allow couples to predict the most fertile days in the cycle. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. With the fast progression in reproductive medicine and the experiences gained through infertility management, a wider range of treatment options have become available to infertile couples [17-19,21-26,31,36], (Appendix 4). Although relatively uncommon, eating disorders can negatively affect menstruation, fertility, and maternal and fetal well-being. Immunological testing has not been proven to have any value in infertility patients without a history of 2 or more miscarriages. Bromocriptine (Parlodel): This drug inhibits prolactin production.

The use of Epididymal and Testicular Spermatozoa for Intracytoplasmic Sperm Injection: The Genetic Implications for Male Infertility. (PDF, 8 MB) Human Reproduction, 1995. IUI is more commonly done when the man has a low sperm count, decreased sperm motility, or when infertility does not have an identifiable cause. Epididymal Surgery. (PDF, 8 MB) Chapter 8 from textbook, Infertility, 1992. Additionally, transvaginal ultrasound affords the opportunity for your physician to assess the relative number of available eggs.

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Infertility and Impaired Fecundity in the United States, 1982-2010: Data from the National Survey of Family Growth. Radiation therapy: If this is aimed near the reproductive organs, it can increase the risk of fertility problems. 6 The initial history should cover menstrual history, timing and frequency of intercourse, previous use of contraception, previous pregnancies and outcomes, pelvic infections, medication use, occupational exposures, substance abuse, alcohol intake, tobacco use, and previous surgery on reproductive organs.

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Isolated LH deficiency (fertile eunuch) In these patients, LH levels are decreased while FSH levels are within the reference range. Successful Pregnancy after Microsurgical Transplantation of an Intact Ovary. (PDF, 438 KB) The New England Journal of Medicine, 2008. Mannitol Induced Central Nervous System Toxicity in Renal Failure. (PDF, 4 MB) Investigative Urology, 1972. Embryo Development after ICSI Using Testicular, Epididymal and Ejaculated Spermatozoa. (PDF, 2 MB) Frontiers in Endocrinology, 1995.

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The only disadvantage with BBT is that in many instances, the shift does not occur in a clear way, and the patient misses the time of ovulation. The woman is instructed to measures her body temperature every morning as soon as she wakes up, before she gets out of bed or before she eats or drinks anything. History-taking Couples with infertility problem should be interviewed separately as well as together, to bring out important facts that one partner might not wish to disclose to the other. In vitro fertilization (IVF). In this technique, your doctor places into your uterus that were fertilized in a dish. This pill generally is taken from menstrual cycle days 3 – 7. 25 Women with no clear risk of tubal obstruction should be offered hysterosalpingography to screen for tubal occlusion and structural uterine abnormalities. Human menopausal gonadotropin, or hMG (Repronex): This contains both FSH and LH. Non-steroidal anti-inflammatory drugs (NSAIDs): Long-term use of aspirin or ibuprofen may make it harder to conceive. It is important to establish whether or not the couple really wants to have a child. Only 5-10% of these couples eventually achieve a pregnancy within 5 years. Three regions have been described, called azoospermic factors a, b, and c (AZFa, AZFb, AZFc).[24] These deletions are observed in 3-19% of patients with idiopathic infertility and 6-14% of patients with oligospermia, although up to 7% of patients with other known causes of infertility may also be found to have a deletion. Microsurgery in Clinical Urology. (PDF, 5 MB) Urology, 1975. Chronic conditions: These include AIDS or cancer.