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Tumors Cancers and nonmalignant tumors can affect the male reproductive organs directly, through the glands that release hormones related to reproduction, such as the pituitary gland, or through unknown causes. Minimal Ovarian Stimulation (mini-IVF) for IVF Utilizing Vitrification and Cryopreserved Embryo Transfer. (PDF, 406 KB) Reproductive BioMedicine Online, 2010.

Problems with sperm If a man makes too few sperm or none at all, the woman cannot become pregnant. Infertility is due to hypogonadotropic hypogonadism. Based on numerous prospective randomized controlled trials, the approach has proven to be beneficial in reducing post-operative morbidities such as wound infections and incisional hernias (especially in morbidly obese patients), and is now deemed safe when applied to surgery for cancers such as cancer of colon.[6][7] Laparoscopic instruments. These sperm show a high level of retained cytoplasmic droplets around the mid piece.

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This abnormality is usually surgically corrected in infancy. If the woman is aged over 35 years, the couple may wish to see a doctor earlier, because fertility testing can take time, and female fertility starts to drop when a woman is in her 30s. Debate: Are Spermatid Injections of any Clinical Value? (PDF, 6 MB) Human Reproduction, 1998. About one-third of infertility cases are caused by fertility problems in men and another one-third of fertility problems are due to fertility problems in women.

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Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous–Palaeogene boundary. (PDF, 238 KB) Biology Letters, 2010. Hypothyroidism: Low thyroid hormone levels--can cause poor semen quality, poor testicular function and may disturb libido.  May be caused by a diet high in iodine.  Reducing iodine intake or beginning thyroid hormone replacement therapy can elevate sperm count.  This condition is found in only 1 percent of infertile men. Fertilizing Capacity of Epididymal and Testicular Sperm using Intracytoplasmic Sperm Injection (ICSI). (PDF, 7 MB)Reproduction, Fertility and Development, 1995.

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Many cases are treated with medication or may require surgical procedures. Gonadotropins can trigger ovulation when Clomid or Serophene don't work. Treatment options available for any particular infertile couple will depend also on the duration of their infertility, which partner is affected, the age of the female partner and if any has a previous children or not, the underlying pathological cause, and if the treatment will be covered by the National Health System (NHS) or funded by their own. However, intercourse 3 times a week results in a probability of conception around 50% within 6 months. Thalassemia Patients with thalassemia have ineffective erythropoiesis and undergo multiple blood transfusions. Women receiving fertility treatment have a slightly higher risk of an ectopic pregnancy. Torsion: Is a common problem affecting fertility that is caused by a supportive tissue abnormality which allows the testes to twist inside the scrotum which is characterized by extreme swelling.  Torsion pinches the blood vessels that feed the testes shut which causes testicular damage.  If emergency surgery is not performed to untwist the testes, torsion can seriously impair fertility and cause permanent infertility if both testes twist. In this case, your doctor may recommend surgically extracting sperm from part of your reproductive tract to help you to conceive. The effects of age on fertility are moderate and do not begin to take an effect until the late 30s. IUI is more commonly done when the man has a low sperm count, decreased sperm motility, or when infertility does not have an identifiable cause. 8  A normal sample according to the 2010 World Health Organization (WHO) guidelines is described in Table 2. Dealing with Fertility Problems After Vasectomy Reversal. (PDF, 7 MB) Contemporary OB/GYN, 1978. B.: - GnRHa should not be offered with ovulation induction for risk of OHSS. - No evidence for the role of adjuvant growth hormones. Controversies in OB/GYN: Is Varicocelectomy Useful for Treatment of Male-factor Infertility? (PDF, 4 MB)Contemporary OB/GYN, 2001.