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Diet: A lack of folic acid, iron, zinc, and vitamin B-12 can affect fertility. The testes are at risk for both thermal and physical trauma because of their exposed position.

At this point, psychological consultation and support should be provided [44]. Some medications increase the risk of fertility problems in men. They can interfere with implantation or block the fallopian tube, preventing sperm from fertilizing the egg.

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Abundant Gene Conversion Between Arms of Palindromes in Human and Ape Y Chromosomes. (PDF, 340 KB)Nature, 2003. If oligospermia or azoospermia is noted, hypogonadism should be suspected. Successful Pregnancy after Microsurgical Transplantation of an Intact Ovary. (PDF, 438 KB) The New England Journal of Medicine, 2008. High-cost treatments are out of financial reach for some couples.

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Normal motility is defined as more than 60% of sperm having normal movement, and the WHO 2010 lower reference limit (5th percentile) is 40%. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. 10 Data Sources: A PubMed search was completed using the key terms infertility, subfertility, treatment, etiology, and diagnosis. Treatment of Female Infertility: Ovulation Induction Agents The main agents used for the induction of ovulation include: Clomiphene citrate is an orally active, nonsteroidal agent structurally similar to estrogen.

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Cervical insemination has almost been abandoned because of its low success and has been relegated only to cases in which the sperm count is normal, such as in artificial insemination using donor sperm or if the sample has elevated white cells. Irregular ovulation can be due to many issues, including polycystic ovary syndrome (PCOS), obesity, being underweight, and thyroid issues. First-line therapy is the ultrasound-guided transvaginal puncture. Perspectives on infertility consultations in primary care: a qualitative study. Quantitative Evaluation of Spermatogenesis by Testicular Histology in Men with Congenital Absence of the Vas Deferens Undergoing Epididymal Sperm Aspiration. (PDF, 3 MB) Human Reproduction, 1990. It could be related to hormone issues, to endometriosis, or to other underlying conditions that could also be contributing to infertility. The effect of age upon men's fertility is less clear.[citation needed] In people going forward for IVF in the UK, roughly half of fertility problems with a diagnosed cause are due to problems with the man, and about half due to problems with the woman. The FAST study: fertility assessment and advice targeting lifestyle choices and behaviours: a pilot study.


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Infertility Boston
Infertility Events
Flower for Infertility