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For men, a visual inspection of sexual characteristics can identify such endocrinopathies as hypogonadism (a condition resulting in atrophy or deficient development of secondary sexual characteristics) or Klinefelter’s syndrome (a genetic anomaly often associated with infertility). Infertility rates have increased by 4% since the 1980s, mostly from problems with fecundity due to an increase in age.[72] Fertility problems affect one in seven couples in the UK. Healthcare providers may also conduct a semen analysis to check the number, shape, and movement of sperm.

Intrauterine insemination is performed during a natural cycle or after ovulation induction with CC or gonadotropins. The patient's electrolyte levels must be checked to consider the need for diuretics.

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Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988–1989). 8-Mb Deletion in the Azoospermia Factor c Region. (PDF, 332 KB) Genomics, 2004.

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Fluctuations in hormone levels can cause: unexplained weight gain severe acne cold feet and hands reduced sex drive or loss of sexual desire nipple discharge facial hair in females thinning hair on the top of the head Underlying medical conditions Other contributing factors that may affect fertility in women include: damage to the fallopian tubes or ovaries premature menopause PCOS endometriosis cancer and cancer treatments Obesity A 2018 study found that obesity might negatively affect reproductive health. The epididymis is a coil-like structure in the testicles which helps store and transport sperm.

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Causes of Infertility Affecting Both Partners Some causes of infertility, such as psychological causes, may be relevant to both partners. While it may be difficult to detect infertility symptoms outright, here are some signs that may point to fertility issues: Irregular periods: The average woman’s cycle is about 28 days long. 3,4  Infertility may arise from male factors, female factors, or a combination of these (Table 15–8). Transmission of Male Infertility to Future Generations: Lessons from the Y Chromosome. (PDF, 303 KB) Human Reproduction Update, 2002. Thankfully, even when the cause of infertility is not known, various fertility treatments can overcome the unknown road block that was preventing pregnancy and eventually lead to delivery of a healthy baby.