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In-Vitro Fertilization (IVF) Image: “Assisted Reproductive Technology” by BruceBlaus. The gonadotropins in these formulations are FSH, and in some cases, a combination of FSH and LH (luteinizing hormone).

Assisted conception The following methods are currently available for assisted conception. 0.[44] Environmental factors Toxins such as glues, volatile organic solvents or silicones, physical agents, chemical dusts, and pesticides.[45][46] Tobacco smokers are 60% more likely to be infertile than non-smokers.[47] German scientists have reported that a virus called adeno-associated virus might have a role in male infertility,[48] though it is otherwise not harmful.[49] Other diseases such as chlamydia, and gonorrhea can also cause infertility, due to internal scarring (fallopian tube obstruction).[50][51][52] Alimentary habits[53] Obesity: The obesity epidemic has recently become is a serious issue, particularly in industrialized nations. This was set up on 1 August 1991 following a detailed commission of enquiry led by Mary Warnock in the 1980s A similar model to the HFEA has been adopted by the rest of the countries in the European Union.

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18  If the semen analysis result is abnormal, further evaluation is indicated (Table 36–8,10,19,20). The HSG is usually scheduled between days 6 and 13 of the cycle - after bleeding and before ovulation. 3) Insemination: Intrauterine insemination, also known as IUI, is a process by which sperm is washed and prepared for placement into the uterine cavity, therefore bypassing the cervix and bringing a higher concentration of motile sperm closer to the tubes and ovulated egg. Artificial Insemination In this process, male sperm is introduced into the female genital tract in order to achieve fertilization. Drugs used for both women and men[67] include clomiphene citrate, human menopausal gonadotropin (hMG), follicle-stimulating hormone (FSH), human chorionic gonadotropin (hCG), gonadotropin-releasing hormone (GnRH) analogues, aromatase inhibitors, and metformin. View Media Gallery Uterine synechiae Uterine synechiae are corrected using operative hysteroscopy.

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Infertility tests for women A woman will undergo a general physical examination, and the doctor will ask about her medical history, medications, menstruation cycle, and sexual habits. There are many disorders that may impact the ability for a woman to ovulate normally. 3) Tubal occlusion (blockage): As discussed previously, a history of sexually transmitted infections including chlamydia, gonorrhea, or pelvic inflammatory disease can predispose a woman to having blocked fallopian tubes. The testicles will be checked for lumps or deformities, and the shape and structure of the penis will be examined for abnormalities.

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Treatment[edit] Treatment depends on the cause of infertility, but may include counselling, fertility treatments, which include in vitro fertilization. Worldwide, 8 to 12 percent of couples experience fertility problems. Primary sterility exists when the couple has never fallen pregnant and secondary sterility when the issue arises following one successful pregnancy but no further pregnancies. For women aged 35, about 94% who have regular unprotected sexual intercourse get pregnant after three years of trying. Treatment of the cause: 24. Ovulation disorders: (Group I) - Weight gain if BMI less than 19. - pulsatile administration of gonadotrophin-releasing hormone or gonadotrophins with luteinising hormone activity to induce ovulation. Cervical surgery can also sometimes cause scarring or shorten the neck of the womb (the cervix). Undescended testicles During fetal development one or both testicles may fail to descend from the abdomen into the sac that normally contains the testicles. Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes. (PDF, 1 MB) Cell, 2009. IVF in action Intracytoplasmic sperm injection (ICSI): A single sperm is injected into an egg to achieve fertilization during an IVF procedure. The procedure is performed by interventional radiology and requires overnight admission for the patient. [125] It is NOT intended for patients who desire fertility. This drug is administered in a pulsatile fashion every 60-120 minutes, intravenously or subcutaneously using a delivery pump. It is usually not the natural state of a healthy adult, except notably among certain eusocial species (mostly haplodiploid insects).