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World Health Organization[edit] The World Health Organization defines infertility as follows:[10] United States[edit] One definition of infertility that is frequently used in the United States by reproductive endocrinologists, doctors who specialize in infertility, to consider a couple eligible for treatment is: a woman under 35 has not conceived after 12 months of contraceptive-free intercourse. Intrauterine insemination 33. Consider unstimulated intrauterine insemination as a treatment option in the following groups as an alternative to vaginal sexual intercourse: - people who are unable to, or would find it very difficult to, have vaginal intercourse - people with conditions that require specific consideration in relation to methods of conception (for example, after sperm washing where the man is HIV positive) - people in same-sex relationships Do not offer IUI for people with unexplained infertility, mild endometriosis or mild male factor. Always take in consideration the ages of the couple. Intra-uterine insemination for unexplained subfertility.

GnRH analog ([GnRHa], leuprolide acetate, nafarelin acetate, goserelin acetate) causes down-regulation of the pituitary, inducing chemical menopause after injections of 3. Transmission of Male Infertility to Future Generations: Lessons from the Y Chromosome. (PDF, 303 KB) Human Reproduction Update, 2002. Recombination Between Palindromes P5 and P1 on the HUman Y Chromosome Causes Massive Deletions and Spermatogenic Failure. (PDF, 786 KB) The American Journal of Human Genetics, 2002. Further backup measures are sufficient thrombosis prophylaxis with heparin and the support of the renal function.

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Intracytoplasmic sperm injection is a process by which semen is washed and prepared for direct injection of one sperm into each egg collected during the IVF process. In humans, infertility is the inability to become pregnant after one year of intercourse without contraception involving a male and female partner.[2] There are many causes of infertility, including some that medical intervention can treat.[3] Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility.

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Often, but not always, submucosal fibroids can cause heavy periods, or bleeding between periods. 4 IU per L]) can help differentiate between primary and secondary disorders. Ovulation disorders appear to be the most common cause of infertility in women. On Regenerating the Ovary and Generating Controversy. (PDF, 37 KB) Cell, 2005. Some facts about conception and fertility A doctor can give advice and carry out some preliminary assessments. Microsurgery and Andrology. (PDF, 5 MB) Chapter from textbook, 1991.

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Signs and Symptoms of Infertility Signs and symptoms of infertility are often related to other underlying conditions. Debate over whether health insurance companies (e.g. in the US) should be required to cover infertility treatment. A low testosterone level with a low FSH level signals a secondary cause. Women with anovulation may be treated in the primary care setting with clomiphene to induce ovulation. Programming of Ovarian Stimulation with Norethindrone Acetate in IVF/GIFT Cycles. (PDF, 2 MB) Human Reproduction, 1989. Microsurgery Successful in Vasectomy Reversals. (PDF, 156 KB) The New York Times, 1975. Women trying to conceive often have depression rates similar to women who have heart disease or cancer.[18] Emotional stress and marital difficulties are greater in couples where the infertility lies with the man.[19] Older people with adult children appear to live longer.[20] Why this is the case is unclear and may dependent in part on those who have children adopting a healthier lifestyle, support from children, or the circumstances that led to not having children.[20] [edit] In many cultures, inability to conceive bears a stigma. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Epidemiological definition of infertility (for monitoring and surveillance) Women of reproductive age (15–49 years) at risk of becoming pregnant (not pregnant, sexually active, not using contraception and not lactating) who report trying unsuccessfully for a pregnancy for two years or more. (Reproductive Health Indicators) Infertility as a disability Disability: Infertility generates disability (an impairment of function), and thus access to health care falls under the Convention on the Rights of Persons with Disability. Primary vs. secondary infertility[edit] Primary infertility is defined as the absence of a live birth for women who desire a child and have been in a union for at least 12 months, during which they have not used any contraceptives.[14] The World Health Organisation also adds that 'women whose pregnancy spontaneously miscarries, or whose pregnancy results in a still born child, without ever having had a live birth would present with primarily infertility'.[15] Secondary infertility is defined as the absence of a live birth for women who desire a child and have been in a union for at least 12 months since their last live birth, during which they did not use any contraceptives.[15] Thus the distinguishing feature is whether or not the couple have ever had a pregnancy which led to a live birth. Linthicum, Md.: American Urological Association, Inc.; 2010. The treatment approach depends on the cause(s) of the infertility. Causes in women Infertility in women can also have a range of causes. In this condition, semen ejaculates backwards into the bladder instead of out the penis.