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The etiology is unknown but is probably multifactorial. This results in an inability to accurately judge how much force is being applied to tissue as well as a risk of damaging tissue by applying more force than necessary. Chlamydia test: Chlamydia can affect fertility, but antibiotics can treat it. Affected individuals displayed more severe forms of infertility such as azoospermia and severe oligozoospermia.[27] Other causes[edit] Factors that can cause male as well as female infertility are: DNA damage DNA damage reduces fertility in female ovocytes, as caused by smoking,[28] other xenobiotic DNA damaging agents (such as radiation or chemotherapy)[29] or accumulation of the oxidative DNA damage 8-hydroxy-deoxyguanosine[30] DNA damage reduces fertility in male sperm, as caused by oxidative DNA damage,[31] smoking,[28] other xenobiotic DNA damaging agents (such as drugs or chemotherapy)[32] or other DNA damaging agents including reactive oxygen species, fever or high testicular temperature.[33] The damaged DNA related to infertility manifests itself by the increased susceptibility to denaturation inducible by heat or acid [34] or by the presence of double-strand breaks that can be detected by the TUNEL assay.[35] General factors Diabetes mellitus,[36][37] thyroid disorders,[38] undiagnosed and untreated coeliac disease,[39][40][41][42] adrenal disease[43] Hypothalamic-pituitary factors Hyperprolactinemia Hypopituitarism The presence of anti-thyroid antibodies is associated with an increased risk of unexplained subfertility with an odds ratio of 1. The Intra-abdominal Testes: Microvascular Autotransplantation. (PDF, 4 MB) The Journal of Urology, 1981.

8 Women in group I typically present with amenorrhea and low gonadotropin levels, most commonly from low body weight or excessive exercise. Infection An increased number of white blood cells in the semen may be observed in patients with infectious or inflammatory processes of the genital tract. Existing definitions of infertility lack uniformity, rendering comparisons in prevalence between countries or over time problematic.

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Kidney Transplantation in Inbred Rats. (PDF, 6 MB) The American Journal of Surgery, 1973. Dr Freundl from the University of Heidelberg suggests that tests which use LH as a reference often lack sensitivity and specificity.[13] Classification[edit] The World Health Organization criteria for classification of anovulation include the determination of oligomenorrhea (menstrual cycle >35 days) or amenorrea (menstrual cycle > 6 months) in combination with concentration of prolactin, follicle stimulating hormone (FSH) and estradiol (E2). Thus women whose pregnancy spontaneously miscarries, or whose pregnancy results in a still born child, without ever having had a live birth would present with primarily infertility. (Trends in prevalence4).

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The rest of the time, it is because of both partners or no cause can be found. 41 Treatment of Unexplained Infertility Jump to section + Couples who have no identified cause of infertility should be counseled on timing of intercourse for the most fertile period (i.e., the six days preceding ovulation).

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If a blockage is present, surgery may be necessary. Sterilisation Some women choose to be sterilised if they don't want to have any more children. The Intra-abdominal Testes: Microvascular Autotransplantation. (PDF, 4 MB) The Journal of Urology, 1981. If each step has occurred as planned, implantation of the fertilized egg into the uterus can take place within 72 hours of the ICSI process. The hypothalamus acts on the false information that the estrogen level in circulation is low, increasing production of FSH and LH, thus stimulating follicular growth. The chance of a multiple birth is lower with an oral fertility drug. LINDSAY, MD, Saint Louis University Family Medicine Residency, Belleville, Illinois KIRSTEN R. Epididymal Surgery. (PDF, 8 MB) Chapter 8 from textbook, Infertility, 1992. The embryo is then placed in the uterus to begin a pregnancy. The rising number of obese individuals may be due in part to an energy-rich diet as well as insufficient physical exercise.  In addition to other potential health risks, obesity can have a significant impact on male and female fertility. Silent Sorority: A Barren Woman Gets Busy, Angry, Lost and Found.Causes of infertility and sterility In 30% of all cases, the cause is in the female partner.