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Causes of Female Infertility (Continued) Other causes of female infertility include: Local factors in the uterus and cervix, including uterine septum, uterine fibroids and endometriosis. 2012;27(8):2396–2404.   Want to use this article elsewhere? A laparoscopy can check the ovaries, fallopian tubes, and uterus for disease. They can include: Changes in hair growth Changes in sexual desire Pain, lump, or swelling in the testicles Problems with erections and ejaculation Small, firm testicles   When to See the Doctor If you are under 35 and have been trying to get pregnant without success for a year, see your doctor. Seminoma Discovered in Two Males Undergoing Successful Testicular Sperm Extraction for Intracytoplasmic Sperm Injection. (PDF, 807 KB) Human Reproduction, 1995.

Use of clomiphene citrate in infertile women: a committee opinion. She will also undergo a gynecologic examination and a number of tests: Laparoscopy involves inserting a thin tube with a camera on to investigate and possibly remove unwanted tissue. Additional risk factors may include smoking, alcohol use, obesity, and older age; however, the data are hampered by a lack of pregnancy-related outcomes. In fact, the “window of opportunity” for fertilization is thought to last only a few hours, thus requiring sperm availability in the female genital tract at or shortly before ovulation. ARTICLES FROM THE 2000s Evaluation and Treatment of Male Infertility. (PDF, 17 MB) Clinical Obstetrics and Gynecology, 2000.

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As treatment begins, couples may experience cycles of optimism and despair with each passing menstrual cycle. This improves the chances that the embryo will implant at, or attach to, the wall of the uterus. Testicular histology typically reveals a decreased number of Leydig cells and decreased spermatogenesis.

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Eating disorders such as anorexia nervosa are also associated with extremely low BMI. If pregnancy has not been established within a reasonable time, further evaluation and/or an alternative treatment plan should be considered. If the correction is not done, it may be harder for the sperm to get to the female's cervix. Evaluation of cervical mucus is unreliable; therefore, investigation is not helpful with the management of infertility. It varies with the age (the optimal female age is between 23 and 39 years) and with body weight (the ideal body mass index is between 19 and 30). Biopsy reveals maturation arrest or germ cell aplasia.

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Individual tests evaluate only one aspect of a quality necessary for fertility and do not imply the ability or inability to achieve conception (see the Table in the Procedures section). Cystic Fibrosis and Infertility Caused by Congenital Bilateral Absence of the Vas Deferens and Related Clinical Entities. (PDF, 2 MB) Human Reproduction, 1996. Infertility may be caused by blockage of the Fallopian tube due to malformations, infections such as chlamydia or scar tissue. Theoretically, with this therapy, we can get artificial gamets in vitro. What Forms of Male Infertility are there left to Cure? (PDF, 2 MB) Human Reproduction, 1995.